Everything about Flaccid Paralysis totally explained
Flaccid paralysis is a
clinical manifestation characterized by
weakness or
paralysis and reduced
muscle tone without other obvious cause (for example,
trauma).
Causes
Polio
The term
acute flaccid paralysis (AFP) is often used to describe a sudden onset, as might be found with polio.
AFP is the most common sign of acute
polio, and used for
surveillance during polio outbreaks. AFP is also associated with a number of other
pathogenic agents including
enteroviruses,
echoviruses, and
adenoviruses, among others.
Botulism
The
Clostridium botulinum bacteria are the cause of
botulism. Vegetative cells of
C. botulinum may be injested. Introduction of the bacteria may also occur via
endospores in a wound. When the bacteria is
in vivo they induce flaccid paralysis. This happens because
C. botulinum produces a toxin which blocks the release of
acetylcholine. When this occurs, the muscles are unable to contract.
Other
Flaccid paralysis can be associated with a
lower motor neurone lesion. This is in contrast to a
upper motor neurone lesion, which often presents with
spastic paralysis.
Included in AFP's list are Poliomyelitis, Transverse myelitis,
Guillain-Barré syndrome, enteroviral encephalopathy, traumatic neuritis,
Reye's syndrome etc.
An AFP Surveillance programme is conducted to increase case yield of poliomyelitis. This includes collection of 2 stool samples within 14 days of onset of paralysis and identification of virus. and control of the outbreak and strenghthening immunisation in that area.
Further Information
Get more info on 'Flaccid Paralysis'.
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